amyotrophic lateral sclerosis

On the Robust Automatic Computation of Speaking and Articulation Duration in ALS Patients Versus Healthy Controls

Speaking and articulation duration have been shown to be important biomarkers of disorder severity in ALS and other motor speech disorders. While signal processing algorithms afford significant advantages over manual annotation in that they allow for …

Multimodal Dialog Based Speech and Facial Biomarkers Capture Differential Disease Progression Rates for ALS Remote Patient Monitoring

Continuous monitoring of ALS symptoms is crucial to improve quality of life because both survival and progression rate can vary substantially between individuals. Speech and facial biomarkers can serve as useful proxies for disease progression and …

Voice Activity Detection Considerations in a Dialog Agent for Dysarthric Speakers

Conversational dialog technology is increasingly being recognized as auseful means of automating remote patient monitoring and diagnostics for dysarthric speakers at scale. However, the characteristics of dysarthric speech introduce multiple …

Investigating the Utility of Multimodal Conversational Technology and Audiovisual Analytic Measures for the Assessment and Monitoring of Amyotrophic Lateral Sclerosis at Scale

We propose a cloud-based multimodal dialog platform for the remote assessment and monitoring of Amyotrophic Lateral Sclerosis (ALS) at scale. This paper presents our vision, technology setup, and an initial investigation of the efficacy of the …